These detectors are selective, sensitive, and reliable, but require conducting mobile phases free of dissolved oxygen and reducible metal ions. For maximum flexibility in quantitative work, this range should be about three orders of magnitude. The subsequent flow of solvent moves the drug down the column in the manner described. Any excess pressure is released as necessary. L31A strong anion-exchange resin-quaternary amine bonded on latex particles attached to a core of 8.5-m macroporous particles having a pore size of 2000. In gas-solid chromatography, the solid phase is an active adsorbent, such as alumina, silica, or carbon, packed into a column. Supports for analysis of polar compounds on low-capacity, low-polarity liquid phase columns must be inert to avoid peak tailing. L20Dihydroxypropane groups chemically bonded to porous silica particles, 5 to 10 m in diameter. When a new test, procedure,or acceptance criterion is added to an existing monograph using a flexible monograph approach, a For manual measurements, the chart should be run faster than usual, or a comparator should be used to measure the width at half-height and the width at the base of the peak, to minimize error in these measurements. The system suitability and acceptance criteria in monographs have been set using parameters as defined below. concentrations of Reference Standard, internal standard, and analyte in a particular solution. Empower currently reports EP Plate Count and JP Plate Count, both of which use peak width at half height (Figure 3). For a perfectly Gaussian peak, the front half-width will be exactly half the entire peak width, so the tailing factor will be 1.0. . The control preparation can be a standard preparation or a solution containing a known amount of analyte and any additional materials useful in the control of the analytical system, such as excipients or impurities. Alternatively, a two-phase system may be used. L30Ethyl silane chemically bonded to totally porous silica particles, 3 to 10 m in diameter. Since the natural water content of the paper, or selective imbibition of a hydrophilic component of the liquid phase by the paper fibers, may be regarded as a stationary phase, a partitioning mechanism may contribute significantly to the separation.
Glasgow, Gorbals 1950s, Articles U